NeuroscienceNaturePeer-reviewed
Prion-like transmission of human tau strains in the mouse brain
Sofia Lövestam, Aki Shimozawa, Airi Tarutani…·Sjors H. W. Scheres
This study demonstrates that tau filaments from Alzheimer's and corticobasal degeneration patients can seed the formation of structurally identical mouse tau filaments, supporting the prion-like transmission hypothesis.
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