Megan Bergkessel

Polyhydroxyalkanoate carbonosomes impact the activity and viability of growth-arrested Pseudomonas aeruginosa during nutrient fluctuations and tobramycin exposure

This study investigates how carbonosomes in Pseudomonas aeruginosa affect cell viability and antibiotic sensitivity during nutrient fluctuations and tobramycin exposure.

Bacterial Aminopeptidase-Activated Peptide Prodrug Enables Species-Selective Targeting of Pseudomonas aeruginosa

This paper designs and tests aminopeptidase-activated AMP prodrugs that selectively target Pseudomonas aeruginosa, showing improved antimicrobial activity and reduced cross-resistance.

The transcriptional regulator SutA is part of a nutrient scavenging network expressed at the entry to stationary phase in Pseudomonas aeruginosa

This paper identifies regulators of SutA expression in Pseudomonas aeruginosa, showing SutA is part of a nutrient scavenging network that coordinates protein synthesis and motility during nutrient limitation.

A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system

This paper identifies a new family of T6SS pore-forming effectors in Serratia marcescens, showing distinct ion selectivity and broader target range compared to existing toxins.

Analyses of protein expression and genetic fitness determinants reveal dynamic pathways active in starved Pseudomonas aeruginosa

This study identifies dynamic protein synthesis and fitness determinants in starved Pseudomonas aeruginosa, revealing distinct physiological strategies and key regulatory functions during carbon and nitrogen starvation.

The dormancy-specific regulator, SutA, is intrinsically disordered and modulates transcription initiation in Pseudomonas aeruginosa

This paper investigates how SutA, a small protein in Pseudomonas aeruginosa, modulates transcription initiation during growth arrest by interacting with RNA polymerase.