Author

Sean A. Uryu

Pfizer (United States)ORCID 0009-0002-8813-1488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrea GillespieiD· 1 shared Anelya MuratiD· 1 shared Antonia D. BoyeriD· 1 shared Benjamin J. BlythiD· 1 shared Brendon J. MonahaniD· 1 shared Christine JeaniD· 1 shared Dane VassiliadisiD· 1 shared Daniela Vanessa WengeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Andrea GillespieORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedJun 19, 2025

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia

Shellaina J.V. Gordon, Florian Perner, Laura MacPherson…·Mark A. Dawson

The paper shows that inhibiting KAT6/KAT7 enhances Menin inhibitor efficacy and overcomes resistance in MLL-FP leukemia.

31 citationstop 1%

humanexperimental assay

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Cell BiologyMolecular Biology of the CellPeer-reviewedApr 9, 2025

Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice

Xiao Lei Chen, Marjaana Ojalill, Christine Jean…·David D. Schlaepfer

The paper shows that deleting FAK in endothelial cells of PYK2-null mice activates p53, suppresses tumor growth, and limits metastasis, while FAK inhibition has different effects.

5 citations

mouseexperimental assay

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