Author

Daniela Vanessa Wenge

Boston Children's HospitalORCID 0000-0002-0064-9104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Scott A. ArmstrongiD· 3 shared Charlie HattoniD· 2 shared Abby M. Thornhill· 1 shared Alessio CiulliiD· 1 shared Alex KentsisiD· 1 shared Ali KhalighifariD· 1 shared Andrea GillespieiD· 1 shared Anelya MuratiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Scott A. ArmstrongORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity

James B. Shaum, Miquel Muñoz i Ordoño, Erica A. Steen, Daniela Vanessa Wenge, Hakyung Cheong, Jordan Janowski, Moritz Hunkeler, Eric M. Bilotta, Zoe J. Rutter, Paige A. Barta, Abby M. Thornhill, Natalia Milosevich, Lauren M. Hargis, Timothy R. Bishop, Trever R. Carter, , Michael A. Erb

This study uses high-throughput chemistry to discover chemical inducers of proximity by modifying pre-existing ligands and screening for degrader activity.

Nature Chemical Biology · Feb 16, 2026Peer-reviewedBiochemistry

Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia

Shellaina J.V. Gordon, Florian Perner, Laura MacPherson, Katie A. Fennell, Daniela Vanessa Wenge, Wallace Bourgeois, Tabea Klaus, Thomas Plenge, Anelya Murat, Jelena Petrovic, Jakub Horvath, Joan Q. Cao, John D. Lapek, Sean A. Uryu, Jeffrey R. White, , Mark A. Dawson

The paper shows that inhibiting KAT6/KAT7 enhances Menin inhibitor efficacy and overcomes resistance in MLL-FP leukemia.

Cancer Discovery · Jun 19, 2025Peer-reviewedCancer Biology

MOZ and HBO1 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia

Nicole Lynn Michmerhuizen, Emily Heikamp, Ilaria Iacobucci, Masayuki Umeda, Bright Arthur, Vibhor Mishra, Chun Shik Park, Danika Di Giacomo, Ryan Hiltenbrand, Qingsong Gao, Sandi Radko-Juettner, Josi Lott, Cynthia Martucci, Varsha Subramanyam, Charlie Hatton, , Charles Grenfell Mullighan

This study identifies MOZ and HBO1 as molecular dependencies in NUP98-rearranged AML, showing their inhibition reduces leukemic burden and synergizes with Menin inhibitors.

Cancer Discovery · Jun 19, 2025Peer-reviewedCancer Biology