Author

Christine Jean

University of California San DiegoORCID 0000-0002-6936-289XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Antonia D. BoyeriD· 1 shared David D. SchlaepferiD· 1 shared David Tarin· 1 shared Duygu OzmadenciiD· 1 shared Dwayne G. StupackiD· 1 shared Isabelle TancioniiD· 1 shared Joseph SchlessingeriD· 1 shared Marjaana OjalilliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Antonia D. BoyerORCID

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1 paper

Recent·Most cited

Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice

Xiao Lei Chen, Marjaana Ojalill, Christine Jean, Isabelle Tancioni, Shulin Jiang, Antonia D. Boyer, Duygu Ozmadenci, Sean A. Uryu, David Tarin, Joseph Schlessinger, Dwayne G. Stupack, David D. Schlaepfer

The paper shows that deleting FAK in endothelial cells of PYK2-null mice activates p53, suppresses tumor growth, and limits metastasis, while FAK inhibition has different effects.

Molecular Biology of the Cell · Apr 9, 2025Peer-reviewedCell Biology