Soluble and insoluble dietary fibres differentially affect liver steatosis and gut microbiota in western-diet fed mice
Céline Marie Pauline Martin, Mathilde Miquel, Valérie Alquier‐Bacquie, Arnaud Polizzi, Frédéric Lasserre, Marine Huillet, Clémence Rives, Justine Bruse, Julie Jarrasier, Prunelle Perrier, Joana Gomes, Claire Naylies, Charlène J. G. Dauriat, Nancy Geoffre, Anaelle Durbec, , Sandrine Ellero‐Simatos
This study shows that soluble fiber inulin reduces liver fat and metabolic issues in mice on a Western diet, while insoluble fiber cellulose does not, suggesting inulin's benefits come from its effect on gut microbiota.
bioRxiv · Nov 26, 2025 · PreprintPhysiology