Molecular BiologyNature Structural & Molecular BiologyPeer-reviewed
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
Hugo Sepúlveda, Xiang Li, Leo J. Arteaga-Vazquez…·Anjana Rao
This study shows that OGT inhibits TET activity, preventing DNA demethylation and transposable element expression in heterochromatin.
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