Paola Manara

This paper identifies GAK as a novel mitotic kinase and therapeutic target in DLBCL, showing that GAK inhibition causes mitotic defects and that existing drugs can be repurposed for its targeting.

This study shows mitochondrial translation is sensitive to ATP synthase activity, with matrix GTP availability identified as a key constraint.

This study shows that inhibiting cap-dependent translation in lymphoma cells increases sensitivity to ferroptosis and CAR-T therapy by reducing NRF2 expression.