Author

Nikolai S. Fattakhov

University of MiamiORCID 0000-0001-6707-9727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Austin Daniel NewsamiD· 2 shared Daniel BilbaoiD· 2 shared Francesco MauraiD· 2 shared Jonathan Harry SchatziD· 2 shared Paola ManaraiD· 2 shared Venu Venkatarame Gowda SaralammaiD· 2 shared Abdessamad A. Youssfi· 1 shared Abdessamad Youssfi AlaouiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Austin Daniel NewsamORCID

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3 papers

Recent·Most cited

NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy

Paola Manara, Austin Daniel Newsam, Venu Venkatarame Gowda Saralamma, Tyler Andrew Cunningham, Drew Lazenby, J.J.David Ho, Marco Vincenzo Russo, Abdessamad Youssfi Alaoui, Dhanvantri Chahar, Alicia Bilbao Martinez, Nikolai S. Fattakhov, Alexandra Marie Carbone, Olivia Barbara Farag, Alexa Marie Barroso, Kyle S. Hoffman, , Jonathan Harry Schatz

This study shows that inhibiting cap-dependent translation in lymphoma cells increases sensitivity to ferroptosis and CAR-T therapy by reducing NRF2 expression.

Cancer Research · Jul 31, 2025Peer-reviewedCancer Biology

RHOA Deletion Downregulates CD19 and Promotes Dysfunctional Immune Microenvironments in CAR-T Resistant B-Cell Lymphoma

Austin Daniel Newsam, Bachisio Ziccheddu, Abdessamad A. Youssfi, Venu Venkatarame Gowda Saralamma, Yitzhar E. Goretsky, Isaiah Sheffield-Veney, Paola Manara, Daniel E Tsai, Adithi Jeevan, Santiago Foos-Russ, David M. Suissa, Marco Vincenzo Russo, Nikolai S. Fattakhov, David Carmona-Berrio, Natalia Campos Gallego, , Jonathan Harry Schatz

bioRxiv · Feb 27, 2025 · PreprintCancer Biology

Lmx1a is a master regulator of the cortical hem.

Igor Y. Iskusnykh, Nikolai S. Fattakhov, Yiran Li, Laure Bihannic, Matthew K. Kirchner, Ekaterina Y. Steshina, Paul A. Northcott, Victor V. Chizhikov

The paper identifies Lmx1a as a master regulator that coordinates the formation and function of the cortical hem, a signaling center critical for hippocampus development.

eLife · Sep 6, 2023Peer-reviewedNeuroscience