Jillella Mallikarjun

This study investigates BSH activity in human gut bacteria and finds that some strains can directly dehydrogenate conjugated bile acids to produce conjugated secondary bile acids, challenging the idea that deconjugation is a prerequisite for further modifications.

The paper shows engineered antisense RNAs in bacteria generate R-loops that disrupt genome integrity, confirming Rho's role in preventing toxic R-loops.