Author

Yean Ming Chew

University of WarwickORCID 0009-0003-6342-1822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Robert Anthony CrossiD· 2 shared Alica Dodoková· 1 shared Arya KrishnaniD· 1 shared Carsten JankeiD· 1 shared Denisa OndruskovaiD· 1 shared Jiří MikšátkoiD· 1 shared Manjari Prakash· 1 shared Marcus BrauniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Robert Anthony CrossORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 15, 2026

Mutating the interprotofilament interface allows microtubules to assemble in GDP

Yean Ming Chew, Robert Anthony Cross

The paper shows that microtubules can assemble in GDP by mutating the interprotofilament interface, suggesting that stable interprotofilament bonds, not GTP bias, drive dynamic instability.

DOI 10.64898/2026.07.09.737542

humanproteomics

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Cell BiologybioRxivPreprintMar 12, 2025

Tubulin isotypes polymerise into sectioned microtubules that locally regulate protein binding

Manjari Prakash, Yean Ming Chew, Denisa Ondruskova…·Marcus Braun

The paper shows that co-polymerization of different tubulin isotypes creates sectioned microtubules that differentially bind MAPs like TPPP1 and OPTN.

3 citations

humanprotein structure

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