Arya Krishnan

Microtubule remodeling by the innate immune factor Trim69 compromises dynein-dependent migration of HIV virion cores towards the nucleus

The paper shows Trim69 remodels microtubules to inhibit HIV virion core migration by stalling dynein/dynactin complexes.

Tubulin isotypes polymerise into sectioned microtubules that locally regulate protein binding

The paper shows that co-polymerization of different tubulin isotypes creates sectioned microtubules that differentially bind MAPs like TPPP1 and OPTN.

Cell-free Reconstitution Reveals Synergistic Stabilization of Microtubule Doublets by PACRG and FAP20

The paper uses cell-free assays to show PACRG and FAP20 synergistically stabilize microtubule doublets by reducing B-tubule depolymerization and increasing rescue frequency.