Author

Nickole Sigcha‐Coello

Memorial Sloan Kettering Cancer CenterORCID 0009-0003-8553-4414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adrián Acuña-RuíziD· 1 shared Alexander Drilon· 1 shared Anthony Robert GloveriD· 1 shared Bin FangiD· 1 shared Bin XuiD· 1 shared Brian R. UntchiD· 1 shared Dina VukeliD· 1 shared Elisa de StanchinaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrián Acuña-RuízORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyMolecular OncologyPeer-reviewedNov 5, 2025

Dual targeting of RET and SRC synergizes in RET fusion-positive cancer cells

Juhyeon Son, Lily L. Remsing Rix, Bin Fang…·Uwe Rix

This study shows that combining RET and SRC inhibitors enhances anti-cancer effects in RET fusion-positive cancers by suppressing PAK signaling and restoring sensitivity in resistant cells.

DOI 10.1002/1878-0261.70155

humanproteomics

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Cancer BiologyThe Journal of Experimental MedicinePeer-reviewedJan 14, 2025

RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness.

Gnana Prakasam Krishnamoorthy, Anthony Robert Glover, Brian R. Untch…·James A. Fagin

This study shows that RBM10 loss causes aberrant splicing of cytoskeletal and ECM genes, leading to RAC1 activation and metastatic fitness in thyroid cancer.

13 citations

mousebulk RNA-seq

𝕏 PostBluesky