Bin Fang

This study identifies TROLL-8 as a regulator of fatty acid oxidation in breast cancer, showing its role in promoting tumorigenesis through CPT1A interaction.

This study identifies that CAFs confer ALK inhibitor resistance in EML4-ALK-driven lung cancer through both MET and integrin signaling pathways, and shows that targeting both pathways improves treatment efficacy.

This study shows that combining RET and SRC inhibitors enhances anti-cancer effects in RET fusion-positive cancers by suppressing PAK signaling and restoring sensitivity in resistant cells.

The paper introduces TAT models to predict compound activity using dose-dependent transcriptomic profiles, achieving 51% assay prediction success and validating malaria inhibitor identification.