Cell BiologyEMBO ReportsPeer-reviewed
SIRT2 Mediates Integrated Stress Response by Deacetylating and Stabilizing 4EBP1 to Suppress Translation
Yanlin Zi, Jiaqi Zhao, Miao Wang…·Hening Lin
This study identifies SIRT2 as a regulator of translation by deacetylating and stabilizing 4EBP1, which suppresses protein synthesis under amino acid limitation.
3 citations