Author

Jiaqi Zhao

Cornell UniversityORCID 0009-0004-6264-9072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Hening LiniD· 2 shared Dan HouiD· 1 shared George E. MaioiD· 1 shared Kay F. MacleodiD· 1 shared Leah M. Ziolkowski· 1 shared Miao WangiD· 1 shared Neha AroraiD· 1 shared Richard A. CerioneiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Hening LinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

SIRT2 Mediates Integrated Stress Response by Deacetylating and Stabilizing 4EBP1 to Suppress Translation

Yanlin Zi, Jiaqi Zhao, Miao Wang, Dan Hou, Richard A. Cerione, Hening Lin

This study identifies SIRT2 as a regulator of translation by deacetylating and stabilizing 4EBP1, which suppresses protein synthesis under amino acid limitation.

EMBO Reports · May 18, 2026Peer-reviewedCell Biology

DHHC7 palmitoylates KRAS4A and promotes mutant KRAS-driven pancreatic cancers

Wenzhe Chen, George E. Maio, Xiao Chen, Xuan Lü, Jiaqi Zhao, Neha Arora, Yinong Liu, Leah M. Ziolkowski, Kay F. Macleod, Yong Zhou, Hening Lin

This study identifies DHHC7 as a palmitoyl transferase that modifies KRAS4A, enhancing its membrane localization and activation, and shows that targeting DHHC7 inhibits pancreatic tumor growth.

bioRxiv · Apr 2, 2026 · PreprintCancer Biology