Author

Adé la Brzobohatá

University of ZurichORCID 0009-0004-0147-2322Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adelheid Wöhrer· 1 shared Albert JeltschiD· 1 shared Angelo DipasqualeiD· 1 shared Anna Sophie BerghoffiD· 1 shared Bart A. WestermaniD· 1 shared Bas WeeninkiD· 1 shared Bauke YlstraiD· 1 shared Frederick S. VarniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adelheid Wöhrer

Mutual co-authors in cluster

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1 paper

Recent·Most cited

TET CpG sequence context specific DNA demeth-ylation shapes progression of IDH-mutant gliomas

Youri Hoogstrate, Santoesha A. Ghisai, Levi van Hijfte, Rania Head, Iris J. de Heer, Marta Padovan, Maurice de Wit, Wies Vallentgoed, Angelo Dipasquale, Maarten M.J. Wijnenga, Bas Weenink, Rosa Luning, Sybren L. N. Maas, Adé la Brzobohatá, Michael Weller, , Pim J. French

The paper identifies DNA methylation changes during IDH-mutant glioma progression, links them to TET enzyme activity, and develops a methylation-based grading system that outperforms WHO grading.

Cell Reports Medicine · Mar 1, 2026Peer-reviewedCancer Biology