Martina Begnis

This study identifies evolutionarily recent transcription factors that influence human cell cycle regulation by affecting gene expression and replication timing.

The paper shows that a transposable element-derived domain in KRAB zinc-finger proteins enables new transcription factor functions through trimerization and condensate formation.

This study identifies ZNF274's role in anchoring lineage-specific gene clusters within repressive perinucleolar compartments, revealing its impact on chromatin structure and gene regulation.