Wenxuan Zhao

The paper develops an automated image analysis pipeline for wide-field optical redox imaging of patient-derived cancer organoids, achieving high accuracy and significantly faster processing than manual methods.

This study uses optical metabolic imaging to show neutrophils rapidly shift to a reduced redox state upon activation, with heterogeneous responses across cells and donors.

This study shows that GATA1-deficient iPSC-derived neutrophils have enhanced antifungal activity against Aspergillus fumigatus, mediated by CD18 integrin.