Morgan A. Giese

Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems

This study uses optical metabolic imaging to show neutrophils rapidly shift to a reduced redox state upon activation, with heterogeneous responses across cells and donors.

GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18

This study shows that GATA1-deficient iPSC-derived neutrophils have enhanced antifungal activity against Aspergillus fumigatus, mediated by CD18 integrin.

Real time imaging reveals a role for macrophage protrusive motility in melanoma invasion

This study uses real-time imaging in zebrafish to show that macrophage protrusive motility, regulated by Rac2, influences melanoma invasion.

Staphylococcus aureus lipid factors modulate melanoma clustering and invasion in zebrafish

This study shows that S. aureus supernatant increases melanoma invasion in zebrafish, likely mediated by bacterial lipids.