Author

Michel V. Levesque

Boston Children's HospitalORCID 0009-0004-2794-3583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew KuoiD· 2 shared Timothy HlaiD· 2 shared Alan Yi-Hui HsuiD· 1 shared Andréane CartieriD· 1 shared Anja NitzscheiD· 1 shared Avishek GhoshiD· 1 shared Christer BetsholtziD· 1 shared Eric CamereriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Andrew KuoORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 28, 2026

Sphingosine 1-phosphate receptor-1 signaling enhances neutrophil survival while suppressing inflammation and bacterial host defense functions

Yueh‐Chien Lin, Takahiro Seno, Alan Yi-Hui Hsu…·Timothy Hla

This study shows that S1PR1 signaling in neutrophils enhances their survival and reduces inflammation but impairs bacterial clearance and protects against lung injury in viral infections.

DOI 10.64898/2026.02.05.703783

mouseexperimental assay

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Molecular BiologyeLifePeer-reviewedFeb 24, 2020

Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta

Eric Engelbrecht, Michel V. Levesque, Liqun He…·Timothy Hla

The paper characterizes S1PR1-regulated transcriptomes in aortic endothelial cells, revealing distinct subtypes and signaling mechanisms in arterial and lymphatic endothelium.

50 citations

mousebulk RNA-seq

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