Author

Mackenzie A Simms

The University of Texas at DallasORCID 0009-0004-3087-8700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ashley N. PlumbiD· 1 shared Gregory O. DussoriD· 1 shared Jane M BrandoniD· 1 shared Joseph B. LesnakiD· 1 shared Katelyn E. SadleriD· 1 shared Katie T. Ward· 1 shared Kevin Joseph TidgewelliD· 1 shared Lucia M Cardona· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ashley N. PlumbORCID

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1 paper

Recent·Most cited

Antibiotics modulate activity of mouse and human dorsal root ganglia neurons

Ashley N. Plumb, Joseph B. Lesnak, Jane M Brandon, Lucia M Cardona, Mackenzie A Simms, McKenna L. Pratt, Katie T. Ward, Kevin Joseph Tidgewell, Gregory O. Dussor, Theodore John Price, Katelyn E. Sadler

The paper shows that antibiotics like β-lactams, macrolides, and tetracyclines alter calcium flux in DRG neurons through mechanisms involving extracellular calcium, TRPA1, and mitochondrial ROS.

bioRxiv · Sep 16, 2026 · PreprintNeuroscience