Author

Jia Shin

Gladstone InstitutesORCID 0009-0004-4760-7333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:electronic health records· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Jorge J. PalopiD· 3 shared Stephanie R. MilleriD· 3 shared Ayushi AgrawaliD· 2 shared Dakota D. Mallen· 2 shared Erica S BradyiD· 2 shared Inma CobosiD· 2 shared Jessica Herbert· 2 shared Kelli LauderdaleiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Jorge J. PalopORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 6, 2026

Therapeutic targeting of fibrin-microglia interactions ameliorates Alzheimer disease-related hyperexcitability and brain network dysfunction

Kelli Lauderdale, Zhaoqi Yan, Andrew S. Mendiola…·Jorge J. Palop

This study shows that blocking fibrin-microglia interactions reduces AD-related brain network dysfunction and behavioral issues in mice.

1 citation

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 30, 2026

Long Wake/Short Sleep Bouts and Hyperactivity with Advanced Age in a Mouse Model of Early Onset Alzheimers Disease

Ryan K. Tisdale, Yu Sun, Stephanie R. Miller…·Thomas S. Kilduff

This paper investigates sleep and activity patterns in a mouse model of early onset Alzheimer's disease, finding a long wake/short sleep phenotype more pronounced in females.

DOI 10.64898/2025.12.29.696818

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 11, 2025

APOE4-Aβ synergy drives brain network dysfunction and neuronal lysosomal-ER proteostasis dysregulation in preclinical Alzheimer's disease

Jia Shin, Erica S Brady, Chun Chen…·Jorge J. Palop

This study investigates how APOE4 and Aβ interact in preclinical Alzheimer's disease, finding their synergistic effects on neuronal proteostasis and network dysfunction.

DOI 10.1101/2025.11.11.687887

mouseexperimental assay

𝕏 PostBluesky