Luca Brenker

This paper introduces ProDomino, a machine learning tool for predicting domain insertion sites in proteins, validated experimentally in E. coli and human cells to create opto- and chemogenetic switches.

This paper develops a versatile platform for optogenetic and chemogenetic control of CRISPR-Cas9 and Cas12 across multiple orthologs using engineered anti-CRISPR proteins.

This paper develops an in vitro transcription-based biosensing workflow to quantify glycolate production in the CETCH cycle, showing high correlation with LC-MS at lower cost and faster speed.