Author

Abbey A. Saadey

The Ohio State UniversityORCID 0009-0004-8473-1288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hazem E. GhoneimiD· 2 shared Amal O. AmeriD· 1 shared Amir YousifiD· 1 shared Amy WebbiD· 1 shared Andrew J. McNamaraiD· 1 shared Ankita SainiiD· 1 shared Asmaa BadriD· 1 shared Asmaa M. Yousif· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Hazem E. GhoneimORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ImmunologyJCI InsightPeer-reviewedOct 7, 2025

Faithful Modeling of Terminal CD8 T Cell Dysfunction and Epigenetic Stabilization In Vitro

Amir Yousif, Abbey A. Saadey, Ava M. Lowin…·Hazem E. Ghoneim

This study develops an in vitro model of terminal CD8 T cell dysfunction and epigenetic stabilization, revealing stable exhaustion signatures and impaired functionality.

11 citationstop 5%

mousescRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 30, 2023

DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates neuroinflammation and amyloid-β deposition in Alzheimer's disease

Kylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy…·Amal O. Amer

This study identifies DNA hypomethylation of CASP4 in AD microglia leading to increased CASP4 expression, which promotes neuroinflammation and amyloid-β deposition in Alzheimer's disease.

4 citations

humanmouse

𝕏 PostBluesky