Author

Fabian Klötzer

University of StuttgartORCID 0009-0004-9567-9112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Markus RehmiD· 2 shared Nadine PollakiD· 2 shared Anna BaatziD· 1 shared Batuhan KısakoliD· 1 shared Daniel B. LongleyiD· 1 shared Fiona GintyiD· 1 shared Gavin FullstoneiD· 1 shared Jenny GeigeriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

Markus RehmORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 9, 2026

Spatiotemporal dynamics of Mcl-1 abundance and its influence on apoptosis susceptibility

Fabian Klötzer, Nadine Pollak, Anna Baatz…·Markus Rehm

This study shows Mcl-1 accumulation and redistribution during the cell cycle increase MOMP thresholds, contributing to cell-to-cell variability in apoptosis susceptibility and intra-tumour heterogeneity.

DOI 10.64898/2026.02.06.704006

humanexperimental assay

𝕏 PostBluesky

Cell BiologyCell Death and DiseasePeer-reviewedDec 19, 2025

Stochasticity contributes to explaining minority and majority MOMP during apoptosis

Jenny Geiger, Fabian Klötzer, Nadine Pollak…·Markus Rehm

This study shows stochasticity in protein distributions and interactions contributes to heterogeneity in mitochondrial MOMP during apoptosis, affecting both minority and majority MOMP scenarios.

4 citations

biophysical modelingcell signaling & trafficking

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