Gavin Fullstone

This study shows stochasticity in protein distributions and interactions contributes to heterogeneity in mitochondrial MOMP during apoptosis, affecting both minority and majority MOMP scenarios.

This study investigates how LRP1 mediates transport across blood-brain barrier endothelial cells, showing that ligand avidity influences cargo sorting and trafficking mechanisms.

The paper introduces FaST, a tool for parallelising agent-based models of cell signalling on CPUs or GPUs, demonstrating performance improvements of 5.8x and 53.9x.