Author
Max Planck Institute of Molecular PhysiologyORCID 0009-0005-2072-0771Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mario O Caracci, Birga Soetje, Luis Manuel Munoz-Nava…·Philippe I.H. Bastiaens
The paper investigates how EGF and EREG influence early oncogenic transformation in intestinal organoids by altering crypt and villus development.
Luis Manuel Muñoz-Nava, Maria Bespalova, Mario O. Caracci…·Philippe I. H. Bastiaens
This paper develops a reversible Opto-Chemical system to activate KRASG12V signaling with near single-cell precision and demonstrates its effects on epithelial transformation.
Birga Soetje, Hui Ma, Sarah Imtiaz…·Philippe I. H. Bastiaens
This study uses a chemical-optogenetic approach to control β-catenin activity in mouse small intestinal organoids, revealing persistent aberrant phenotypes and altered differentiation during homeostasis.
Mario O. Caracci, Sabrina Seidler, Luis Manuel Muñoz-Nava…·Philippe I. H. Bastiaens
This study shows that EGF and EREG ligands regulate proliferation and differentiation in mouse intestinal organoids by modulating EGFR endocytosis and surface expression.