Author
Max Planck Institute of Molecular PhysiologyORCID 0000-0002-6724-1314Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Mario O Caracci, Birga Soetje, Luis Manuel Munoz-Nava…·Philippe I.H. Bastiaens
The paper investigates how EGF and EREG influence early oncogenic transformation in intestinal organoids by altering crypt and villus development.
Luis Manuel Muñoz-Nava, Maria Bespalova, Mario O. Caracci…·Philippe I. H. Bastiaens
This paper develops a reversible Opto-Chemical system to activate KRASG12V signaling with near single-cell precision and demonstrates its effects on epithelial transformation.
Birga Soetje, Hui Ma, Sarah Imtiaz…·Philippe I. H. Bastiaens
This study uses a chemical-optogenetic approach to control β-catenin activity in mouse small intestinal organoids, revealing persistent aberrant phenotypes and altered differentiation during homeostasis.
Mario O. Caracci, Sabrina Seidler, Luis Manuel Muñoz-Nava…·Philippe I. H. Bastiaens
This study shows that EGF and EREG ligands regulate proliferation and differentiation in mouse intestinal organoids by modulating EGFR endocytosis and surface expression.
Maitreyi S. Joshi, Angel Stanoev, Birga Soetje…·Philippe I. H. Bastiaens
The paper shows RPTPγ suppresses promigratory EGFR signaling by redox regulation, enabling phosphorylation responses to low EGF levels while blocking spontaneous signaling.