Author

Sarah Isler

Ottawa Institute of Systems BiologyORCID 0009-0005-2470-2327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Ànnia Carré SimoniD· 1 shared Cecilia Martuzzi· 1 shared Damien D’AmoursiD· 1 shared Emmanuelle FabreiD· 1 shared Guillaume LaflammeiD· 1 shared Henrik Dahl PinholtiD· 1 shared Juan RegueraiD· 1 shared Leonid A. MirnyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ànnia Carré SimonORCID

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1 paper

Recent·Most cited

Cell BiologyiSciencePeer-reviewedAug 1, 2026

Smc5/6 - microtubules binding shapes pericentromeric chromatin

Ànnia Carré Simon, Cecilia Martuzzi, Sarah Isler…·Emmanuelle Fabre

This study shows that Smc5/6 microtubule binding constrains chromatin dynamics and promotes pericentromeric folding in yeast, safeguarding genome stability during mitosis.

DOI 10.1016/j.isci.2026.116943

yeastDNA methylation

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