Cancer BiologybioRxivPreprint
Regnase-1 Promotes Tumor-Initiating Activity in Non-Small Cell Lung Cancer
Keito Okazaki, Madoka Kawaguchi, Shohei Murakami…·Hozumi Motohashi
This study shows Regnase-1 promotes tumor-initiating activity in NSCLC by suppressing the SOX2 pathway, and its inhibition reduces tumor growth and enhances anti-cancer immunity.
DOI 10.1101/2025.07.08.663650