Author

Yaroslav E. Abramenko

Russian Academy of SciencesORCID 0009-0005-2946-3257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexandra V. BruteriD· 1 shared Alvina I. KhamidullinaiD· 1 shared Anna V. TvorogovaiD· 1 shared Nataliya G Pavlenko· 1 shared Tamara A Kiryukhina· 1 shared Victor Vyacheslavovich TatarskiyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Alexandra V. BruterORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 23, 2025

Eg5 Inhibitor SB743921 Causes p53-Dependent Cell Cycle Arrest, Senescence and Death in Tumor Cells

Yaroslav E. Abramenko, Alvina I. Khamidullina, Tamara A Kiryukhina…·Victor Vyacheslavovich Tatarskiy

This study shows that the Eg5 inhibitor SB743921 induces p53-dependent cell cycle arrest, senescence, and death in tumor cells, particularly in TP53-mutated cells, with potential for combinational therapy with senolytic drugs.

DOI 10.1101/2025.01.23.634373

humanexperimental assay

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