Dingxun Wang

The paper analyzes the evolutionary history and embryonic expression of KCNH voltage-gated potassium channels in zebrafish, revealing their origins in invertebrates and expanded gene numbers in vertebrates.

The paper identifies Piezo3 as a new PIEZO paralog in vertebrates, shows its mechanosensitive function in HEK293T cells, and demonstrates its role in zebrafish mechanosensation and light response.

This paper identifies PRMT5 as a therapeutic target in MTAP-deficient MPNSTs, showing that its inhibition suppresses cell growth and enhances DNA damage when combined with chemotherapy.

This study identifies Kir7.1's role in maintaining membrane potential and directional sensing during neutrophil chemotaxis, showing its necessity for polarized depolarization and chemotactic movement.