Notash Shafiei

This paper uses cryo-ET to study amyloid fibrils in neurodegenerative brain tissue, revealing ultrastructural details of fibril polymorphs and their association with disease.

This study uses correlative light and electron microscopy to characterize the ultrastructural changes in tau fibrils during ghost tangle formation in Alzheimer's disease brain tissue.

This study uses correlative light and electron microscopy to analyze Lewy body pathology in Parkinson's and dementia with Lewy bodies, revealing regional differences in ultrastructure and mitochondrial changes.

The paper examines ultrastructural differences between somatic and neuritic Lewy body inclusions in Parkinson's disease using correlative light and electron microscopy.

The paper determines the cryo-EM structure of alpha-synuclein fibrils with the E83Q mutation, revealing structural changes linked to enhanced aggregation and pathogenicity.

This paper provides a protocol for correlative light and electron microscopy (CLEM) optimized for analyzing human brain tissue, enabling detailed ultrastructural analysis and characterization of subcellular features.