Author

Isabel Korpas

Icahn School of Medicine at Mount SinaiORCID 0009-0005-5392-6960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Abishek Balachandra VaidyaiD· 2 shared Alice Oliffson KamphorstiD· 2 shared Amaia LujambioiD· 2 shared Brad R. RosenbergiD· 2 shared Étienne HumbliniD· 2 shared Nataliya ProkhnevskaiD· 2 shared Verena van der HeideiD· 2 shared Adam R. MarksiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersImmunology

Abishek Balachandra VaidyaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 24, 2026

B cells sustain tumor-specific CD4 T cells to promote response to PD-1 targeted therapy

Abishek Balachandra Vaidya, Étienne Humblin, Nataliya Prokhnevska…·Alice Oliffson Kamphorst

This study shows that B cells support tumor-specific CD4 T cells to enhance PD-1 blockade efficacy, but antibody secretion is not necessary for long-term survival.

DOI 10.64898/2026.09.18.751292

mouseexperimental assay

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ImmunologyImmunityPeer-reviewedSep 20, 2024

ICOS limits memory-like properties and function of exhausted PD-1+ CD8 T cells

Étienne Humblin, Isabel Korpas, Nataliya Prokhnevska…·Alice Oliffson Kamphorst

This study shows ICOS limits the function of exhausted PD-1+ CD8 T cells by promoting their differentiation into less functional effector-like cells, and inhibiting ICOS improves anti-tumor responses.

26 citationstop 5%

mouseflow cytometry

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