Rebecca Pagès

The paper shows tropomodulin and leiomodin nucleate tropomyosin clusters on actin filaments, with tropomodulin acting at the pointed end and leiomodin along the entire filament.

The paper introduces a drag flow method to study protein-protein interactions, showing that low forces detach tropomyosin clusters from actin filaments, with detachment rates depending on isoform and force magnitude.

This study shows that inorganic phosphate (Pi) in the Arp2/3 complex stabilizes actin filament branches, with Pi release rates and force-dependent stability affecting branch stability and regrowth.

This paper develops genetically encoded fluorescent reporters to quantify actin filament organization in living cells and tissues using fluorescence polarization microscopy.