Author

Virginia Sinigiani

ETH ZurichORCID 0009-0005-7761-1074Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Caroline Ashiono· 1 shared Constance CiaudoiD· 1 shared Cristiana BersaglieriiD· 1 shared Ivo ZempiD· 1 shared Juan M. VaquerizasiD· 1 shared Krisztián KoósiD· 1 shared Noura MaziakiD· 1 shared Péter HorváthiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Caroline Ashiono

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1 paper

Recent·Most cited

Cell BiologyNature Cell BiologyPeer-reviewedFeb 24, 2026

LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis

Renard TM Lewis, Virginia Sinigiani, Noura Maziak…·Ulrike Kutay

This study shows that LBR and LAP2 tether heterochromatin to the nuclear periphery, and their loss disrupts genome homeostasis by repositioning heterochromatin and altering gene expression.

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