Author

Caroline Ashiono

ETH Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Assay:proteomics· 1

Frequent Co-Authors

Ulrike KutayiD· 2 shared Alessia LoffredaiD· 1 shared Ashutosh KumariD· 1 shared Constance CiaudoiD· 1 shared Cristiana BersaglieriiD· 1 shared Daria MaslennikovaiD· 1 shared Federico UlianaiD· 1 shared Gautam DeyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Ulrike KutayORCID

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2 papers

Recent·Most cited

LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis

Renard TM Lewis, Virginia Sinigiani, Noura Maziak, Krisztián Koós, Cristiana Bersaglieri, Ivo Zemp, Caroline Ashiono, Constance Ciaudo, Péter Horváth, Juan M. Vaquerizas, Raffaella Santoro, Puneet Kumar Sharma, Ulrike Kutay

This study shows that LBR and LAP2 tether heterochromatin to the nuclear periphery, and their loss disrupts genome homeostasis by repositioning heterochromatin and altering gene expression.

Nature Cell Biology · Feb 24, 2026Peer-reviewedCell Biology

Dystonia-associated Torsins sustain CLCC1 function to promote membrane fusion of the nuclear envelope for NPC biogenesis

Daria Maslennikova, Harry J. M. Baird, Alessia Loffreda, Kausthubh Ramachandran, Ashutosh Kumar, Jelmi uit de Bos, Caroline Ashiono, Katharina Frischer-Ordu, Naemi Luithle, Federico Uliana, Gautam Dey, Stefano Vanni, Madhav Jagannathan, Ulrike Kutay

This study identifies CLCC1 as a Torsin1A binding partner essential for nuclear envelope membrane fusion during NPC biogenesis, showing its therapeutic potential for DYT1 dystonia.

bioRxiv · Nov 7, 2025 · PreprintCell Biology