Ulrike Kutay

This study identifies Brl1 and Brr6 as conserved fusogens mediating membrane fusion during NPC assembly in eukaryotes.

This study uses FluidFM and FLIM to analyze how A-type and B-type lamins and microtubules respond to mechanical and chemical cues, revealing distinct roles in nuclear elasticity and viscous response.

The paper identifies RNF25 as a ribosome collision response pathway that competes with GCN2 in amino acid starvation, resolving stalls independently of GCN2 activation.

This study shows that LBR and LAP2 tether heterochromatin to the nuclear periphery, and their loss disrupts genome homeostasis by repositioning heterochromatin and altering gene expression.

This study identifies CLCC1 as a Torsin1A binding partner essential for nuclear envelope membrane fusion during NPC biogenesis, showing its therapeutic potential for DYT1 dystonia.

This study shows that a phosphodeficient Climp63 mutant causes mitotic delays and nuclear fragmentation by preventing the dissolution of ER-microtubule contacts during mitosis.

The paper identifies a dual key lock mechanism involving RIO1 and RPS26 that controls the final maturation step of 40S ribosomal subunits by displacing DIM2 and enabling NOB1-mediated cleavage of 18S rRNA.

The paper quantifies proteome assembly state changes during mitosis using SEC-SWATH-MS and identifies new mitotic complex disassembly events.