Zachary Matthew Vanwinkle

This paper constructs HUSA, a comprehensive germline resource linking allele diversity to expressed antibody repertoires by integrating long-read sequencing and AIRR-seq data.

The paper develops methodologies to generate and analyze immunoglobulin loci variation in rhesus macaques, revealing extensive diversity and expanding existing allele sets by 60%.

The paper introduces a method using ultra-long sequencing and bioinformatics to resolve haplotypes in the human immunoglobulin heavy chain locus, uncovering novel alleles and structural variants.