Author

Carla S. Maduta

Western UniversityORCID 0009-0005-8916-3619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

John K. McCormickiD· 2 shared Karine DufresneiD· 2 shared Dennis A. DiMaggioiD· 1 shared Emily P Barbosa· 1 shared Erica N. DeJongiD· 1 shared Nicholas R. WaltoniD· 1 shared Shaun R. BrinsmadeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

John K. McCormickORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 6, 2025

Elucidating the Staphylococcus aureus TSST-1 regulatory network as a response to vaginal pH

Carla S. Maduta, Nicholas R. Walton, Emily P Barbosa…·John K. McCormick

This study identifies GraXRS as the main activator of TSST-1 at low pH in Staphylococcus aureus, revealing a complex regulatory network in response to vaginal pH changes.

DOI 10.1101/2025.09.06.674626

humanproteomics

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MicrobiologyJournal of Biological ChemistryPeer-reviewedJun 7, 2024

Discovery of an anti-virulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin 1 (TSST-1) production

Karine Dufresne, Dennis A. DiMaggio, Carla S. Maduta…·John K. McCormick

The paper identifies PP-HCl as an anti-virulence compound that inhibits TSST-1 production in S. aureus without affecting bacterial growth or vaginal microbiota.

17 citationstop 4%

humanmouse

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