Paula Sotillo Sotillo

This study investigates how β-amyloid and tau pathologies affect different neural circuits in a novel Alzheimer's disease mouse model, revealing region-specific synaptic, behavioral, and molecular changes.

The paper shows that 63% of gut microbiome proteins have prion-like sequences that can form amyloid fibrils, impair memory in C. elegans, and may contribute to neurodegenerative diseases.