Anna Heger

This study investigates the role of Pten in radial glial progenitor lineage progression and astrocyte production during cortical development, finding that Pten loss increases astrocyte generation and disrupts growth factor signaling.

This study shows that tissue-wide genetic effects override cell-intrinsic gene function in cortical neuron migration using MADM and single-cell analysis.

The paper introduces a genome-wide MADM mouse library enabling single-cell genetic mosaic analysis and uses it to study chromosome-specific segregation biases in stem cell division.