This study investigates the role of Pten in radial glial progenitor lineage progression and astrocyte production during cortical development, finding that Pten loss increases astrocyte generation and disrupts growth factor signaling.

bioRxiv · May 5, 2026 · PreprintNeuroscience

Adult neural stem cells and neurogenesis are resilient to intermittent fasting

Rut Gabarró‐Solanas, Amarbayasgalan Davaatseren, Justus Kleifeld, Tatjana Kepčija, Thomas Köcher, Albert Giralt, Iván Crespo‐Enríquez, Noelia Urbán

This study investigates the effects of intermittent fasting on adult neural stem cells and neurogenesis in mice, finding no significant impact on NSC activation, maintenance, or neurogenesis.

EMBO Reports · Nov 21, 2023Peer-reviewedNeuroscience

A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis

Ximena Contreras, Nicole Amberg, Amarbayasgalan Davaatseren, Andi H. Hansen, Johanna Sonntag, Lill Andersen, Tina Bernthaler, Carmen Streicher, Anna Heger, Randy L. Johnson, Lindsay A. Schwarz, Liqun Luo, Thomas Rülicke, Simon Hippenmeyer

The paper introduces a genome-wide MADM mouse library enabling single-cell genetic mosaic analysis and uses it to study chromosome-specific segregation biases in stem cell division.

Cell Reports · Jun 1, 2021Peer-reviewedDevelopmental Biology