Author

Jelle Nikkels

Leiden University Medical CenterORCID 0009-0006-2368-2077Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Ingrid MeulenbeltiD· 2 shared Louise van der WeerdiD· 2 shared Luis Javier CruziD· 2 shared Sayedeh Sana SayedipouriD· 2 shared Y.F. RamosiD· 2 shared Bernd GiebeliD· 1 shared Bram C. J. van der EerdeniD· 1 shared Chiara GentiliiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Ingrid MeulenbeltORCID

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2 papers

Recent·Most cited

Molecular BiologyOsteoarthritis and Cartilage OpenPeer-reviewedJun 5, 2026

Evaluating the Therapeutic Efficacy of Iopanoic Acid in a DMM-Induced Osteoarthritis Mouse Model and Osteochondral Lesioned Human Explants

Sayedeh Sana Sayedipour, Giorgia Mazzini, Margo Tuerlings…·Ingrid Meulenbelt

This study evaluates iopanoic acid's therapeutic effects on osteoarthritis using mouse models and human tissue explants, showing reduced cartilage degradation and improved repair.

1 citation

mousehuman

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Developmental BiologybioRxivPreprintAug 20, 2025

Therapeutic efficacy of hiMSC-derived Extracellular Vesicles from Serum-containing and Xeno-free media for osteoarthritis treatment

Sayedeh Sana Sayedipour, Jelle Nikkels, Tobias Tertel…·Y.F. Ramos

This study evaluates the therapeutic effects of hiEVs from different media in an OA mouse model, finding that xeno-free hiEVs reduce joint damage and promote cartilage repair.

1 citation

mouseexperimental assay

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