Author

Tran Do Hoang Nhu

Stanford MedicineORCID 0009-0006-3316-4812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Marwah KarimiD· 3 shared Shirit EinaviD· 3 shared Stefan KnappiD· 2 shared Susanne MülleriD· 2 shared Theresa A. L. Ehret· 2 shared Thomas HankeiD· 2 shared Abhilasha KarkeyiD· 1 shared Aditi AgrawaliD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersBiochemistry

Marwah KarimORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistryEuropean Journal of Medicinal ChemistryPeer-reviewedAug 22, 2025

Development of pyrazolopyrimidine based macrocyclic kinase inhibitors targeting AAK1

Theresa Elisabeth Mensing, Christian Georg Kurz, Jennifer Alisa Amrhein…·Thomas Hanke

The paper develops pyrazolopyrimidine-based macrocyclic kinase inhibitors targeting AAK1, showing selectivity over related NAK family members and antiviral activity against RNA viruses.

4 citations

experimental assaydrug response / drug discovery

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MicrobiologyNature CommunicationsPeer-reviewedJul 10, 2025

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Marwah Karim, Manjari Mishra, Chieh‐Wen Lo…·Shirit Einav

RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.

19 citationstop 1%

humanorganoid / primary culture

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedJul 19, 2024

Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity

Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer…·Thomas Hanke

The paper optimizes a 2-aminopyrimidine-based macrocycle to create a dual EPHA2/GAK kinase inhibitor with antiviral activity against dengue virus.

13 citations

humanexperimental assay

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BioinformaticsCommunications BiologyPeer-reviewedAug 2, 2023

Direct inference and control of genetic population structure from RNA sequencing data

Muhamad Fachrul, Abhilasha Karkey, Mila Shakya…·Michael Inouye

This paper introduces RGStraP, a tool to infer genetic population structure from RNAseq data and shows it can control for population structure in gene expression analyses.

12 citations

humanbulk RNA-seq

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