Author

Meilin Tian

Chinese Academy of SciencesORCID 0009-0006-6220-9506Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein design· 2 Approach:deep learning· 1 Assay:electronic health records· 1 Organism:human· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Zhu ZhuiD· 2 shared Antoine SicardiD· 1 shared Bolin AniD· 1 shared Cécile CardosoiD· 1 shared Cécile CharrieriD· 1 shared Chao ZhongiD· 1 shared Chenli LiuiD· 1 shared Dongmin XuniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersSynthetic Biology

Zhu ZhuORCID

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3 papers

Recent·Most cited

Synthetic BiologyNature CommunicationsPeer-reviewedOct 31, 2026

AI-driven discovery and engineering of human endogenous nanocage proteins for mRNA delivery

Dongmin Xun, Lanqing Li, Jie Zou…·Chao Zhong

The paper develops DeepDelivery, an AI platform that identifies human proteins for mRNA delivery, validating 80% of top candidates for efficient, non-inflammatory delivery.

DOI 10.1038/s41467-026-79039-x

humandeep learning

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Synthetic BiologybioRxivPreprintDec 25, 2025

Engineered translation release factor 1 suppresses disease-causing nonsense mutations and enables multi-site nonstandard amino acids incorporation

Yuting Chen, Meilin Tian, Zhu Zhu…·Chenli Liu

This paper introduces OPENER, an engineered eRF1 variant that suppresses nonsense mutations and enables nonstandard amino acid incorporation, showing therapeutic benefits in a Duchenne muscular dystrophy model.

DOI 10.64898/2025.12.24.695955

mouseexperimental assay

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NeurosciencebioRxivPreprintOct 14, 2024

Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites

Antoine Sicard, Meilin Tian, Zakaria Mostefai…·Laétitia Mony

This study introduces Opto2B, a tool to selectively modulate GluN2B diheteromers, revealing their minor role in synaptic and extrasynaptic NMDAR pools in adult hippocampal CA1 pyramidal cells.

DOI 10.1101/2024.10.14.618157

mouseelectronic health records

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