Author

Yuting Chen

Chinese Academy of SciencesORCID 0000-0003-0436-8876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Chenli LiuiD· 2 shared George McDonald ChurchiD· 2 shared Anlu CheniD· 1 shared Eriona HysolliiD· 1 shared Meilin TianiD· 1 shared Peng Gong· 1 shared Qian Ya· 1 shared Songlei LiuiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSynthetic Biology

Chenli LiuORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintDec 25, 2025

Engineered translation release factor 1 suppresses disease-causing nonsense mutations and enables multi-site nonstandard amino acids incorporation

Yuting Chen, Meilin Tian, Zhu Zhu…·Chenli Liu

This paper introduces OPENER, an engineered eRF1 variant that suppresses nonsense mutations and enables nonstandard amino acid incorporation, showing therapeutic benefits in a Duchenne muscular dystrophy model.

DOI 10.64898/2025.12.24.695955

mouseexperimental assay

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Synthetic BiologyNature CommunicationsPeer-reviewedAug 2, 2022

Multiplex base editing to convert TAG into TAA codons in the human genome

Yuting Chen, Eriona Hysolli, Anlu Chen…·George McDonald Church

The paper demonstrates multiplex base editing to convert TAG to TAA codons in 33 essential human genes and introduces a computational tool for recoding.

24 citations

humanexperimental assay

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