Author

Isabelle Pirson

Université Libre de BruxellesORCID 0000-0002-9499-600XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Gayane HovhannisyaniD· 2 shared Sumeet Pal SinghiD· 2 shared Abeer Kaafarani· 1 shared Adèle Herpoel· 1 shared Alexia Gybels· 1 shared Angéline Bilheu· 1 shared Anja van Benthem· 1 shared Anne Lefort· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

Gayane HovhannisyanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Rhpn2 promotes zebrafish melanoma development and aggressiveness in vivo

Mana Alavi, Alexia Gybels, Laura Gulizia, Katarzyna Konobrocka, Gayane Hovhannisyan, Sena Bekar, Camille Perazzolo, Sumeet Pal Singh, Isabelle Pirson

This study shows Rhpn2 promotes zebrafish melanoma development and aggressiveness by enhancing tumor growth and invasion.

bioRxiv · Jul 3, 2026 · PreprintCancer Biology

CellCousin2: An Optimized System for Partial Ablation and Tracing of Regenerative Lineages

Gayane Hovhannisyan, Tawba Akhourbi, Sema Elif Eski, Isabelle Pirson, Esteban N. Gurzov, Sumeet Pal Singh

CellCousin2 improves lineage tracing in zebrafish by reducing background recombination and enhancing ablation efficiency with a new system.

npj Regenerative Medicine · Mar 30, 2026Peer-reviewedDevelopmental Biology

Synaptic Gpr85 influences cerebellar granule cells electrical properties and light-induced behavior.

Romain Darche-Gabinaud, Abeer Kaafarani, Marine Chazalon, Valérie Suain, Erika Hendrickx, Louise Conrard, Anne Lefort, Frédérick Libert, Mehmet Can Demirler, Serge N. Schiffmann, David L. Pérez-Morga, Valérie Wittamer, Marc Parmentier, Isabelle Pirson

This study identifies Gpr85 as a synaptically enriched modulator of neuronal excitability and light-induced behavior in zebrafish.

bioRxiv · Mar 10, 2025 · PreprintNeuroscience

The microcephaly gene ASPM is required for the timely generation of human outer-radial glia progenitors by controlling mitotic spindle orientation

Anja van Benthem, Ridha Limame, Matteo Piumatti, Maurine Zaratin, Emir Erkol, Daisuke H. Tanaka, Adèle Herpoel, Angéline Bilheu, Harmen van Benthem, Laura Nebreda, Isabelle Pirson, Kathelijn Keymolen, Suresh Kumar Poovathingal, Martyna Ditkowska, Julie Désir, , Pierre Vanderhaeghen

This study shows ASPM mutations disrupt mitotic spindle orientation in human cortical progenitors, leading to premature oRGC generation and reduced cortical progenitor numbers.

bioRxiv · Sep 25, 2023 · PreprintNeuroscience