Author

Keerthana Chari

Yale UniversityORCID 0009-0007-0701-8712Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Amy L. StiegleriD· 1 shared Kallol GuptaiD· 1 shared Meera Chari· 1 shared Moitrayee BhattacharyyaiD· 1 shared Rachel A. McAllisteriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Amy L. StieglerORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJun 29, 2026

Two-Step Mechanism of Bruton's Tyrosine Kinase MembraneRecruitment and Activation

Rachel A. McAllister, Amy L. Stiegler, Keerthana Chari…·Kallol Gupta

This paper uses native mass spectrometry to show BTK recruits to membranes via phosphatidylserine and is activated by PIP3, proposing a two-step mechanism for membrane recruitment and activation.

2 citations

proteomicsexperimental assay

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